Rejuran vs Skin Boosters: What Is the Difference in Seoul?
Rejuran is a polynucleotide (PN) injectable aimed at skin repair and texture, while "skin booster" is a broader term for hydrating injectables such as hyaluronic acid. Both are usually done in a series. At The Heal Dermatology Sinsa Main Branch in Gangnam, Seoul, a dermatologist chooses based on your skin's needs and travel plans.
Written by The Heal Dermatology medical content team · Pending review by a board-certified dermatologist · Updated October 2026
What each one is
Rejuran is an injectable based on polynucleotides (PN), DNA fragments derived from salmon, intended to support skin repair, elasticity and texture. "Skin booster" is a broader term used in Korea for injectables that improve hydration and skin quality, most commonly using hyaluronic acid, sometimes combined with other ingredients.
Key differences
- Main purpose: Rejuran is often chosen for texture, fine lines and skin recovery; HA skin boosters are often chosen for hydration and glow.
- Feel: Rejuran injections can be more noticeable; small bumps typically settle within 1–3 days.
- Variants: Rejuran Healer for the face, Rejuran Eye for the delicate under-eye area.
- Combination: some people use both, spaced appropriately, depending on skin needs.
What to expect at The Heal Sinsa
At The Heal Dermatology Sinsa Main Branch, a board-certified dermatologist evaluates your skin's hydration, texture and sensitivity before suggesting Rejuran, an HA skin booster, or another approach. Skin boosters are among the treatments listed by The Heal branches; for specific brands, availability varies by branch – confirm at consultation. Pricing is confirmed after consultation; see pricing and payment.
Sessions and downtime
- Sessions: often around 3 sessions spaced 2–4 weeks apart, then maintenance.
- Downtime: small bumps, redness or bruising for 1–3 days.
- Results: build gradually over the series.
- Avoid makeup on injection points for about a day.
Risks and who should avoid
Possible side effects include temporary bumps, bruising, tenderness and, rarely, infection or allergic reaction. People with fish allergy should discuss Rejuran with their doctor. Injectables are usually postponed during pregnancy and breastfeeding and with active skin infection.
Planning around your trip to Seoul
Because small bumps may be visible for a day or two, plan injections early in your stay. See how many days to plan and Juvelook vs Sculptra.
Questions to ask your dermatologist
Ask which product suits your main concern, how many sessions are realistic, how long bumps or bruising may last and whether it can be combined with lasers or lifting in the same trip. If you have sensitive skin or allergies, raise them before treatment so the plan can be adjusted.
Related
Frequently asked questions
Is Rejuran a skin booster?
In Korea, Rejuran is often grouped with skin boosters because it targets skin quality. However, its main ingredient is polynucleotide rather than hyaluronic acid, so it works differently from typical hydrating boosters.
How long do Rejuran bumps last?
Small injection bumps usually settle within one to three days. Bruising, if it occurs, can take longer. Plan injections early in your trip, before photos or important events. Avoid makeup on injection points for about a day.
Can I have Rejuran if I am allergic to fish?
Rejuran is derived from salmon DNA, so discuss any fish or seafood allergy with your dermatologist before treatment. They may recommend a different option depending on your history. Mention all allergies at consultation.
Planning skin treatment in Seoul?
The Heal Dermatology Sinsa Main Branch is led by Korean board-certified dermatologists. International patient guide · All patient guides · Treatments · Our doctors
Branches: Sinsa (Main) · Jamsil · Dongdaemun · Mapo-Gongdeok
General information only; it does not replace a consultation with a dermatologist.